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"SARS-CoV and the novel SARS-CoV-2 share 79.5% sequence identity" -- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393809/
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#SARS-CoV / #SARS-CoV-1 and #SARS-CoV-2
"Receptor recognition is an important determinant of hCoVs infection and pathogenesis. The specific surface protein that provides the entry door in human cells for both SARS-CoV and SARS-CoV-2 is angiotensin-converting enzyme 2 (ACE2) [17–19]. The first difference between the two SARS-CoVs is that SARS-CoV-2 receptor-binding domain (RBD) has a higher ACE2-binding affinity, a characteristic which could lead to a more efficient cell entry [19]. However, ACE2-binding affinity of the entire SARS-CoV-2 S protein seems to be comparable to or even lower than that of SARS-CoV entire S protein."
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"Conflicting reports on SARS-CoV-2 pathogenicity may also be related to genetic differences in the expression of the SARS-CoV-2 host cell entry factors among individuals and between populations [26, 27]."
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Some viruses' theme song: https://www.youtube.com/watch?v=BaAPAcYNoZs
Pop That Thang
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See also this article from June of 2020: https://pubmed.ncbi.nlm.nih.gov/32275259/
The other article is from July of 2020.
#MERS #SARS #COVID-19 #2019-nCoV #coronavirus #SARS-CoV #SARS-CoV-2 #MERS-CoV